Lymphatic filariasis in western Ethiopia

Wuchereria bancrofti vespid, Immune response, Serum immune complexes diagnosis, Diethylcarbamazine (DEC), Wolbachia in filarial parasites, Interdigital skin lesions, Urban Filariasis, Doxycycline, mass drug administration program, Filarial Lymphedema Care, Detection of filarial parasites, Albendazole, research abstracts

Moderators: jenjay, Cassie, patoco, Birdwatcher, Senior Moderators

Lymphatic filariasis in western Ethiopia

Postby patoco » Wed Dec 21, 2011 3:08 pm

Lymphatic filariasis in western Ethiopia with special emphasis on prevalence of Wuchereria bancrofti antigenaemia in and around onchocerciasis endemic areas.

Dec. 2011

Shiferaw W, Kebede T, Graves PM, Golasa L, Gebre T, Mosher AW, Tadesse A, Sime H, Lambiyo T, Panicker KN, Richards FO, Hailu A.

Source
Department of Microbiology, Immunology and Parasitology (DMIP); Faculty of Medicine, Addis Ababa University, PO Box 9086, Addis Ababa, Ethiopia.

Keywords
Lymphatic filariasis; Wuchereria bancrofti; Ethiopia; Onchocerciasis; Immunochromatographic Test (ICT); Antigenaemia

Abstract
Lymphatic filariasis is known to be endemic in Gambella Region, western Ethiopia, but the full extent of its endemicity in other regions is unknown. A national mapping program for Ethiopia was initiated in 2008. This report summarizes initial data on the prevalence of Wuchereria bancrofti antigenaemia based on surveys carried out in a sampled population of 11685 individuals living in 125 villages (112 districts) of western Ethiopia. The overall prevalence rate was 3.7%, but high geographical clustering and variation in prevalence (ranging from 0% to more than 50%) was found. The prevalence of hydrocele (in males) and lymphoedema of limbs was 0.8% and 3.6% respectively. Significantly higher (χ(2)=49.6; P<0.01) prevalence of antigenaemia was noted in known onchocerciasis endemic districts (4.7%) compared to non-onchocerciasis endemic districts (2.3%). Thirty-four of the 112 districts, with a population of 1547685 in 2007, were found to be endemic. Of these, the numbers of districts with prevalence rates of >20%, 10-20% and 5-9% were nine, 14 and 20 respectively. Twenty-nine of these 34 endemic districts were found in three regions: Gambella Region (seven districts), Beneshangul-Gumuz Region (13 districts), and Southern Nations, Nationalities and Peoples' Region (SNNPR) (nine districts). The other five were from Amhara (two districts) and Oromia (three districts) regions. A tentative distribution map has been drawn to facilitate the launching of the Ethiopia LF elimination program.

Royal Society of Tropical Medicine and Hygiene

http://www.sciencedirect.com/science/ar ... 0311002100
patoco
Site Admin
 
Posts: 2175
Joined: Thu Jun 08, 2006 9:07 pm

Return to Lymphatic Filariasis

Who is online

Users browsing this forum: No registered users and 2 guests