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glossary:antimetabolites

A drug that is similar enough to a natural chemical to participate in a normal biochemical reaction in cells but different enough to interfere with the normal division and functions of cells. So named because the drug inhibits a normal metabolic process. Examples of antimetabolites include 6-mercaptopurine (6MP), methotrexate, and hydroxyurea.

Anticancer drugs that closely resemble substances needed by cells for normal growth. The tumor cells uses the drug instead and “starves” for lack of proper substance.

glossary/antimetabolites.txt · Last modified: 2012/10/16 14:40 (external edit)