Gas Gangrene also called is Clostridial and Myonecrosis. It is caused by Clostridium perfringens(ecrotizing subcutaneous infection). This bacteria is belong to Group A Streptococcus. Clostridium bacteria is produce toxins and it cause tissue death and associated symptoms. It generally occurs at a wound or surgical site, causing painful swelling and destruction of involved tissue. Other common clostridial species that cause gas gangrene include Clostridium bifermentans, Clostridium septicum, Clostridium sporogenes, Clostridium novyi, Clostridium fallax, Clostridium histolyticum, and Clostridium tertium. These environmental bacteria may enter the muscle through a wound and go on to proliferate in necrotic tissue and secrete powerful toxins. These toxins destroy nearby tissue, generating gas at the same time. A gas composition of 5.9% hydrogen, 3.4% carbon dioxide, 74.5% nitrogen and 16.1% oxygen was reported in one clinical caseGas gangrene is rapidly progressive and often fatal. Bacteria in the Clostridium species are gram-positive, spore-forming, anaerobic rods normally found in soil and the gastrointestinal tract of humans and animals.