Closed-space infections of the fingertip pulp. Fingertip pulp is divided into numerous small compartments by vertical septa that stabilize the pad. Infection occurring within these compartments can lead to abscess formation, edema, and rapid development of increased pressure in a closed space. This increased pressure may compromise blood flow and lead to necrosis of the skin and pulp. Staphylococcus aureus is the most common cause. Methicillin-resistant Staphylococcus aureus–infected felons have been reported.
·Gram-negative organisms have been reported in immunosuppressed patients. Fingertip blood glucose measurements have been implicated as an etiology.
·Eikenella corrodens has been reported in persons with diabetes who bite their fingernails