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glossary:imipenem

(1) (Science: chemical) 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7- oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid. Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative bacteria and gram-positive bacteria aerobic and anaerobic organisms]] (bacteria), including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilastatin, a renal dipeptidase inhibitor.

Pharmacological action: thienamycins.

Chemical name: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)

(2) An antibiotic drug used to treat severe or very resistant infection. It belongs to the family of drugs called carbapenems.

See also:

Antibiotics

Antibiotic Glossary

Antibiotics (blog)

glossary/imipenem.txt · Last modified: 2012/10/16 14:40 (external edit)