T cells that express the CD8 transmembrane glycoprotein (CD8+ T cells). They close down the immune response after invading organisms are destroyed. Suppressor T cells are sensitive to high concentrations of circulating lymphokine hormones, and release their own lymphokines after an immune response has achieved its goal. This signals all other immune-system participants to cease their attack. Some memory B-cells remain after this signal to ward off a repeat attack by the invading organism. Also known as T-8 cells.
See also CD8, T cells; T lymphocytes, cytotoxic.